USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: SC23A_HUMAN USC-OGP 2-DE database:  SC23A_HUMAN SC23A_HUMAN General information about the entry View entry in simple text format Entry name SC23A_HUMAN Primary accession number Q15436 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Protein transport protein Sec23A; AltName: Full=SEC23-related protein A;. Gene name Name=SEC23A Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1258: pI=6.30; Mw=30200 Cross-references UniProtKB/Swiss-Prot Q15436; SC23A_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name SC23A_HUMAN Primary accession number Q15436 Secondary accession number(s) B2R5P4 B3KXI2 Q8NE16 Sequence was last modified on  March 6, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 164) Name and origin of the protein Description RecName: Full=Protein transport protein Sec23A; AltName: Full=SEC23-related protein A; Gene name Name=SEC23A Encoded on Name=SEC23A Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Disease mutation; Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Membrane; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Transport. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X97064; CAA65774.1; -; mRNA EMBL AK127355; BAG54494.1; -; mRNA EMBL AK312259; BAG35191.1; -; mRNA EMBL AL109628; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC036649; AAH36649.1; -; mRNA CCDS CCDS9668.1; -. [Q15436-1]; . PIR T09574; T09574; . RefSeq NP_006355.2; NM_006364.3. [Q15436-1]; . UniGene Hs.272927; -; . PDB 2NUP; X-ray; 2.80 A; A=1-765 PDB 2NUT; X-ray; 2.30 A; A=1-765 PDB 2YRC; NMR; -; A=57-108 PDB 2YRD; NMR; -; A=57-108 PDB 3EFO; X-ray; 2.70 A; A=1-765 PDB 3EG9; X-ray; 3.00 A; A=1-764 PDB 3EGD; X-ray; 2.70 A; A=1-764 PDB 3EGX; X-ray; 3.30 A; A=1-764 PDB 5KYN; X-ray; 2.55 A; A/B=1-765 PDB 5KYU; X-ray; 3.51 A; A=1-765 PDB 5KYW; X-ray; 3.20 A; A=1-765 PDB 5KYX; X-ray; 3.52 A; A=1-765 PDB 5KYY; X-ray; 3.40 A; A=1-765 PDBsum 2NUP; -; . PDBsum 2NUT; -; . PDBsum 2YRC; -; . PDBsum 2YRD; -; . PDBsum 3EFO; -; . PDBsum 3EG9; -; . PDBsum 3EGD; -; . PDBsum 3EGX; -; . PDBsum 5KYN; -; . PDBsum 5KYU; -; . PDBsum 5KYW; -; . PDBsum 5KYX; -; . PDBsum 5KYY; -; . ProteinModelPortal Q15436; -; . SMR Q15436; -; . BioGrid 115747; 83; . IntAct Q15436; 51; . MINT MINT-4998885; -; . STRING 9606.ENSP00000306881; -; . iPTMnet Q15436; -; . PhosphoSitePlus Q15436; -; . SwissPalm Q15436; -; . BioMuta SEC23A; -; . DMDM 143811354; -; . EPD Q15436; -; . MaxQB Q15436; -; . PaxDb Q15436; -; . PeptideAtlas Q15436; -; . PRIDE Q15436; -; . DNASU 10484; -; . Ensembl ENST00000307712; ENSP00000306881; ENSG00000100934. [Q15436-1]; . Ensembl ENST00000537403; ENSP00000444193; ENSG00000100934. [Q15436-2]; . GeneID 10484; -; . KEGG hsa:10484; -; . UCSC uc001wup.2; human. [Q15436-1]; . CTD 10484; -; . DisGeNET 10484; -; . GeneCards SEC23A; -; . H-InvDB HIX0011611; -; . HGNC HGNC:10701; SEC23A; . HPA HPA043806; -; . HPA HPA069974; -; . MalaCards SEC23A; -; . MIM 607812; phenotype; . MIM 610511; gene; . neXtProt NX_Q15436; -; . OpenTargets ENSG00000100934; -; . Orphanet 50814; Craniolenticulosutural dysplasia; . PharmGKB PA35624; -; . eggNOG KOG1986; Eukaryota; . eggNOG COG5047; LUCA; . GeneTree ENSGT00390000006916; -; . HOGENOM HOG000231690; -; . HOVERGEN HBG055039; -; . InParanoid Q15436; -; . KO K14006; -; . OMA GDYHKDD; -; . OrthoDB EOG091G063R; -; . PhylomeDB Q15436; -; . TreeFam TF300693; -; . Reactome R-HSA-1655829; Regulation of cholesterol biosynthesis by SREBP (SREBF); . Reactome R-HSA-204005; COPII (Coat Protein 2) Mediated Vesicle Transport; . Reactome R-HSA-2132295; MHC class II antigen presentation; . Reactome R-HSA-5694530; Cargo concentration in the ER; . Reactome R-HSA-983170; Antigen Presentation: Folding; assembly and peptide loading of class I MHC; . ChiTaRS SEC23A; human; . EvolutionaryTrace Q15436; -; . GeneWiki SEC23A; -; . GenomeRNAi 10484; -; . PRO PR:Q15436; -; . Proteomes UP000005640; Chromosome 14; . Bgee ENSG00000100934; -; . CleanEx HS_SEC23A; -; . ExpressionAtlas Q15436; baseline and differential; . Genevisible Q15436; HS; . GO GO:0030127; C:COPII vesicle coat; IEA:InterPro; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0005783; C:endoplasmic reticulum; TAS:ProtInc; . GO GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome; . GO GO:0012507; C:ER to Golgi transport vesicle membrane; TAS:Reactome; . GO GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell; . GO GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl; . GO GO:0030868; C:smooth endoplasmic reticulum membrane; IEA:UniProtKB-SubCell; . GO GO:0008270; F:zinc ion binding; IEA:InterPro; . GO GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome; . GO GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome; . GO GO:0048208; P:COPII vesicle coating; TAS:Reactome; . GO GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:Reactome; . GO GO:0006886; P:intracellular protein transport; IEA:InterPro; . GO GO:0016192; P:vesicle-mediated transport; TAS:ProtInc; . Gene3D 3.40.20.10; -; 1; . Gene3D 3.40.50.410; -; 1; . InterPro IPR029006; ADF-H/Gelsolin-like_dom; . InterPro IPR007123; Gelsolin-like_dom; . InterPro IPR006900; Sec23/24_helical_dom; . InterPro IPR006896; Sec23/24_trunk_dom; . InterPro IPR012990; Sec23_24_beta_S; . InterPro IPR002035; VWF_A; . InterPro IPR006895; Znf_Sec23_Sec24; . Pfam PF00626; Gelsolin; 1; . Pfam PF08033; Sec23_BS; 1; . Pfam PF04815; Sec23_helical; 1; . Pfam PF04811; Sec23_trunk; 1; . Pfam PF04810; zf-Sec23_Sec24; 1; . SUPFAM SSF53300; SSF53300; 1; . SUPFAM SSF81811; SSF81811; 1; . SUPFAM SSF82754; SSF82754; 1; . SUPFAM SSF82919; SSF82919; 1; .

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